Search results for "P cell"

showing 5 items of 5 documents

Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury

2020

Recent studies have indicated oligodendroglial-vascular crosstalk during brain development, but the underlying mechanisms are incompletely understood. We report that oligodendrocyte precursor cells (OPCs) contact sprouting endothelial tip cells in mouse, ferret and human neonatal white matter. Using transgenic mice, we show that increased or decreased OPC density results in cognate changes in white matter vascular investment. Hypoxia promoted both increased OPC numbers and higher white matter vessel density, and endothelial cell expression of the Wnt pathway targets Apcdd1 and Axin2, suggesting paracrine OPC-endothelial signaling. Conditional knockout of OPC Wntless resulted in diminished w…

0301 basic medicineGenetically modified mouseoligodendrocytesMice TransgenicBiologyArticleWhite matter03 medical and health sciencesParacrine signallingMice0302 clinical medicinetip cell angiogenesisAxin ProteinConditional gene knockoutmedicineAXIN2AnimalsHumanshypoxic-ischemic encephalopathyHypoxiaWnt Signaling PathwayGeneral NeuroscienceWnt signaling pathwayFerretsIntracellular Signaling Peptides and ProteinsEndothelial CellsMembrane ProteinsCell DifferentiationHypoxia (medical)Wnt signalingWhite Matter3. Good healthCell biologyEndothelial stem cellstomatognathic diseasesOligodendroglia030104 developmental biologymedicine.anatomical_structurenervous systemEndothelium Vascularmedicine.symptom030217 neurology & neurosurgeryNeuron
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In Vitro Evaluation of the Biological Effects of ACTIVA Kids BioACTIVE Restorative, Ionolux, and Riva Light Cure on Human Dental Pulp Stem Cells

2019

This study aimed to analyze the biological effects of three new bioactive materials on cell survival, migration, morphology, and attachment in vitro. ACTIVA Kids BioACTIVE Restorative (Pulpdent, Watertown, MA, USA) (Activa), Ionolux (Voco, Cuxhaven, Germany), and Riva Light Cure UV (SDI, Bayswater, Australia) (Riva) were handled and conditioned with a serum-free culture medium. Stem cells from human dental pulp (hDPSCs) were exposed to material extracts, and metabolic activity, cell migration, and cell morphology were evaluated. Cell adhesion to the different materials was analyzed by scanning electron microscopy (SEM). The chemical composition of the materials was evaluated by energy-dispe…

Dental materialsCytotoxicityCellGlass ionomer cement02 engineering and technologyCell morphologylcsh:TechnologyOdontologiaArticleBiological properties03 medical and health sciences0302 clinical medicineDental pulp stem cellsdental pulp cellsmedicinedental materialsGeneral Materials ScienceViability assayBioactive materialslcsh:MicroscopyCell adhesionlcsh:QC120-168.85biological propertieslcsh:QH201-278.5lcsh:TChemistrybioactive materialsCell migration030206 dentistry021001 nanoscience & nanotechnologyMolecular biologyDental pulp cellsmedicine.anatomical_structurelcsh:TA1-2040cytotoxicitylcsh:Descriptive and experimental mechanicslcsh:Electrical engineering. Electronics. Nuclear engineeringStem celllcsh:Engineering (General). Civil engineering (General)0210 nano-technologylcsh:TK1-9971Materials
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Morphometry and comparative histology of sinus and atrioventricular nodes in humans and pigs and their relevance in the prevention of nodal arrhythmi…

2019

The cardiac conduction system is a network structure that allows the initiation and fast propagation of electrical impulses that trigger the electrical depolarization of the myocardial tissue. The purpose of this work is to study the histological and morphometric characteristics of the different components of the sinus and atrioventricular nodes in humans and pigs and their relationship with supraventricular arrhythmias. In this study, we describe the morphometry of the sinus and atrioventricular nodes of 10 adult humans and 10 pig hearts. A computerized morphometric study has been carried out, where we determined the number of cells that compose the nodes as well as different parameters re…

Swine040301 veterinary sciencesBiology0403 veterinary science03 medical and health sciencesHeart Conduction SystemmedicineAnimalsHumansdiameter [Area]Intermediate filamentsHeart AtriaHistology Comparativecardiovascular diseasesSinus (anatomy)Sinoatrial Node030304 developmental biology0303 health sciencesSupraventricular arrhythmiaGeneral VeterinaryT cellArrhythmias CardiacHistologyDepolarization04 agricultural and veterinary sciencesAnatomyAtrioventricular nodemedicine.anatomical_structureConduction systemAtrioventricular NodeP cellcardiovascular systemDesminElectrical conduction system of the heartNODALResearch in Veterinary Science
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Manufacturing and characterization of single cell intermediate-temperature solid oxide fuel cells for APU in transportation application

2014

The fabrications of large area IT-SOFC planar cell by new simple and cost effective process were explained. The optimization of the new process with respect to pore formers, thickness of layers, sintering temperature were performed. The electrochemical results of 10cm2 performed in Fiaxell open flange set up were detailed with respect to different configuration. Long term ageing performance tests of single cells were conducted in Fiaxell device and results are discussed. Preparation of new test bench and stacking process performed till now were briefed.

[ PHYS.PHYS.PHYS-CHEM-PH ] Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph]CosinteringIT-SOFCTest benchLong term ageing performanceSingle step cell preparation[PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph]StackTape castingAnode Functional Layer[PHYS.PHYS.PHYS-CHEM-PH] Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph]
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Comparative Surface Morphology, Chemical Composition, and Cytocompatibility of Bio-C Repair, Biodentine, and ProRoot MTA on hDPCs

2020

Biocompatibility is an essential property for any vital pulp material that may interact with the dental pulp tissues. Accordingly, this study aimed to compare the chemical composition and ultrastructural morphology of Biodentine (Septodont, Saint Maur-des-Fosses, France), ProRoot MTA (Dentsply Tulsa Dental Specialties, Johnson City, TN, USA), and Bio-C Repair (Angelus, Londrina, PR, Brazil), as well as their biological effects on human dental pulp cells. Chemical element characterization of the materials was undertaken using scanning electron microscopy and energy dispersive X-ray analysis (SEM-EDX). The cytotoxicity was assessed by analyzing the cell viability (MTT assay), cell morphology …

cytocompatibilityBiocompatibilityvital pulp materialschemistry.chemical_element02 engineering and technologyCalciumCell morphologylcsh:TechnologyArticleFlow cytometry03 medical and health sciences0302 clinical medicinestomatognathic systemdental pulp cellsmedicineGeneral Materials ScienceMTT assayViability assaycalcium silicate materialsCytotoxicitylcsh:Microscopylcsh:QC120-168.85calcium silicate materialmedicine.diagnostic_testlcsh:QH201-278.5Chemistrylcsh:Tdental pulp cell030206 dentistry021001 nanoscience & nanotechnologystomatognathic diseasesendodonticlcsh:TA1-2040Pulp (tooth)lcsh:Descriptive and experimental mechanicslcsh:Electrical engineering. Electronics. Nuclear engineering0210 nano-technologylcsh:Engineering (General). Civil engineering (General)lcsh:TK1-9971Nuclear chemistryMaterials
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